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Discovering small molecule modifiers of zebrafish development and behavior

日期: 2012-09-21

william hill中文网2012学年秋季学期系列学术讲座之二
题目:Discovering small molecule modifiers of zebrafish development and behavior
报告人:Randall Peterson
Associate Professor of Medicine, Harvard Medical School
Senior Associate Member, Broad Institute
时间:2012年9月21日(周五),13:00-14:30 PM
地点:威廉希尔一楼邓祐才报告厅
Abstract:
Whereas small molecule discovery has traditionally focused on simple, in vitro assays, many biological phenomena are difficult to reduce to an in vitro assay. The Peterson lab is using the tools of chemical biology to investigate these complex in vivo phenomena. By conducting high-throughput screens with intact, living zebrafish, small molecules can be discovered that alter virtually any biological process. The lab is applying this approach in three areas: 1) developmental biology, including primordial germ cell development; 2) disease physiology, including heart failure; and 3) animal behaviors. In each of these areas, the novel small molecules discovered are providing new biological insights and/or novel therapeutic opportunities.
联系人:刘东(电话:62753189)
欢迎各位老师和同学积极参加!