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Synaptic signaling of retinoic acidin homeostatic synaptic plasticity and mental disorders

日期: 2017-12-15

威廉希尔学术报告

Title : Synaptic signaling of retinoic acidin homeostatic synaptic plasticity and mental disorders

Speaker : Lu Chen

Professor of Neurosurgery and of Psychiatry and Behavioral Sciences,

Stanford University

Time:  Dec. 23th Sat.10:00-11:00 A.M. ;2017年12月23日周六

Venue: Rm.1206, Kezhen Wang Building;王克桢楼1206 报告厅

Host: Dr. Chen Zhang;张晨研究员

Student  Host: Mengping Wei;魏梦萍 weimengping@pku.edu.cn

Introduction:
The long-term goal of my research is to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation. In this broad research area, we are specifically interested in the molecular underpinnings of activity-dependent regulation of synaptic strength, the role of postsynaptic protein translation in plastic changes of synaptic activity, and the impairment of synapses in autism spectrum disorders (e.g. Fragile X syndrome) that involves changes in postsynaptic protein translation and synaptic strength.
Some of my current research focuses include:
1.Synaptic signaling mechanisms of RA
2.Synaptic dysfunction in Fragile-X Syndrome

3.Oxidative stress and synaptic dysfunction

欢迎各位老师同学积极参加!