IMM & SLS & CLS Research Seminar
Title：Transcriptional regulation in cardiovascular system development and disease
Speaker：William T. Pu, M.D.
Professor of Pediatrics
Department of Cardiology, Boston Children’s Hospital,
Harvard Medical School, USA
Time：2016年6月22日（星期三）下午1:00-2:30
Place：英国威廉希尔公司金光生命科学大楼101报告厅
Host：英国威廉希尔公司分子医学研究所  何爱彬 (Tel. 6276-7275)
Abstract: Formation and function of the cardiovascular system is under exquisite transcriptional control. Using a combination of functional genetic, transcriptomic, and epigenomic approaches the Pu lab has been investigating the molecular mechanisms of transcriptional regulation in the heart and vascular systems. In this talk I will summarize some of the findings: (1) mapping of dynamic changes in transcription factor complexes and binding sites through heart development and disease; (2) post-transcriptional regulation of transcription factor complexes in and their effects on heart growth; and (3) development of a Cre-directed method for cell type specific enhancer identification and its application to studying transcriptional regulation of blood vessel formation and homeostasis.
欢迎各位老师同学积极参加！